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Cocaine is metabolized by the body primarily in the liver, where it is broken down by enzymes such as carboxylesterase 1 (CES1) into its primary metabolites, benzoylecgonine, and ecgonine methyl ester, as studied by the UN Office on Drugs and Crimes in Metabolism of cocaine. These metabolites are less active than cocaine itself and are eventually excreted in the urine

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So Im hopeful that they recognize that not only in South Dakota do we talk about that life but that we also show that we will support them and that these are situations that they often find that they are unexpectedly in, Noem said